![]() John Lazar performed his dissertation research in the Department of Genome Sciences under the mentorship of Dr. He is currently completing the clinical phase of medical school at Morehouse School of Medicine in Atlanta. He found that KDM4D, a demethylase targeting H3K9me3, can reactivate cell cycle gene expression and mitigate cardiac myocyte damage in response to ischemic injury. An epigenetic mechanism limiting cardiac myocyte cycling in adult cardiac myocytes involves trimethylation of lysine-9 of Histone H3 (H3K9me3), a modification associated with repressed chromatin, which silences expression of cell cycle genes and ordinarily restricts heart regeneration following injury. He has pursued a new strategy of coaxing otherwise terminally differentiated cardiac myocytes to re-enter the cell cycle. Freeman’s research is to promote cardiac regeneration in patients after suffering a myocardial infarction. Robb MacLellan in the Division of Cardiology in the Department of Medicine at the University of Washington. He earned his PhD in the Molecular and Cellular Biology interdisciplinary program in the laboratory of Dr. Miles Freeman is a student in the Morehouse School of Medicine/University of Washington MSTP pathway. In another project, David addressed disparities in clinical trials research and developed software to analyze a large clinical trials database. ![]() In one project addressing craniectomy methods, David developed software to perform quantitative image analysis on CT scans. David has continued research while performing clerkships. The neuroprosthetic devices he developed are leading the way to help treat stroke and other brain injuries. David’s research was highly collaborative and involved a summer spent performing research at the University of Freiburg, in Germany. His work was interdisciplinary and involved working with patients undergoing brain surgery, in vitro systems, computational modeling, and electrical device circuit design. David engineered new approaches for targeted direct electrical stimulation of the brain. in the School of Computer Science and Engineering. in the Department of Neurological Surgery and Rajesh Rao, Ph.D. Tribble is a legendary senior executive at Apple and continues to develop health enabling technologies, such as the EKG features of the Apple Watch.ĭavid Caldwell performed his dissertation research in neurosciences through the Department of Bioengineering under the mentorship of Jeffrey Ojemann, M.D. In fact, UW MSTP alum, Bud Tribble, led development of the Apple Macintosh operating system while a student in our program Dr. The UW MSTP has a long history of MSTP students performing computational internships. Katie Liu, to create a smartphone game controlled by skin electrodes recording muscle activity, in order to speed recovery from nerve injuries. While performing clerkships, Jacob has collaborated with MSTP alumnus and surgical resident, Dr. At Google, Jacob developed medical diagnostic machine learning algorithms. This passion led him to perform a summer internship culminating in a one-year position as a software engineer at Google headquarters in Mountain View, California, in-between the conclusion of his dissertation research and before re-entering clerkships. ![]() Shwetak Patel, a Professor in the UW School of Computer Science & Engineering, to apply machine learning to develop a smartphone app to measure pupillary light responses, for traumatic brain injury diagnosis. Concurrent with, yet independently from, his PhD research, Jacob worked with Dr. Jacob has additionally distinguished himself due to an enduring interest in computational science. Employing a multidisciplinary experimental and computational approach, Jacob discovered unexpected heterogeneity among distinct cone cell types in the primate retina, extending throughout all levels of spatial, spectral, and neurocortical organization. Jacob studied the neuroscience of color vision. Fred Rieke, in the Department of Physiology and Biophysics. Jacob Baudin completed his dissertation research under the mentorship of HHMI Investigator, Dr.
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